Cosmetics & Bio-Products: Organic extracts for purer formulations.

Why Cosmetics?

Cosmetic products are complex mixtures of ingredients with different physical, chemical and functional properties formulated in order to obtain the product with desired activity and quality.

Cosmetic product manufacturers can now move from synthetic to plant- based ingredients (also known as ingredients of plant-origin) in order to increase product purity and quality, with the use of the novel Supercritical Fluid CO2 Extraction (SCFE).

The Extraction Advantage

Supercritical Fluid CO2 Extraction is a promising extraction technique that helps replace the organic toxic solvents previously in use in the industry (such as chloroform, dichloromethane, diethyl ether, methanol etc.).

Due to its unique properties, the desirable texture, absence of water or solvent traces, chemical stability and presence of bioactive agents, SCFE extracts can be easily incorporated into cosmetic products. Moreover, SCFE provides a high concentration of bioactive compounds which exhibit many bioactivities in cosmetic products, such as antioxidants, anti-ageing, photo-protective agents or providing antibacterial activity.

SCFE is an environmentally friendly extraction technique based on the application of generally regarded as safe (GRAS) solvent CO2 and high pressures which has many advantages over the conventional processes.

Requirements in Extraction

  • Lower adulteration in extraction process.
  • The extracted solvent should have higher bioactive and lower residues.
  • The output should be chemical free.
  • Multiple recipe selection.
  • Clean, safe and Green Technology.
  • Robust process and monitor controlling.
  • Operational safety.
  • Minimal human intervention.

Buffalo Extraction Systems Solution

Three levels of CO2   SCFE equipment

System Features

01
Accurate Pressure
Control
02
Consistent Flow
Control
03
Superior Sealing
Technology
04
Unique Extractor
Closure Design
05
Special Separator
Design
06
Proprietary Changeover
Valves

Bringing the Future of Extraction to the World

Our team starts by blending principles with practicalities and continue by connecting proven automation process blocks into a holistic solution.

System Specifications

Parameters Level 1 Level 2 Level 3
Single Extractor Volume (Litre) 5 25 100 / 200 / 300
No. of Extractors 2 or 3 2 or 3 2 or 3
Extractors Usage Single Single or Series Single or Series
Pressure Bar (PSI) 350 - 650
(5000 - 9500)
350 - 650
(5000 - 9500)
350 - 650
(5000 - 9500)
Temperature — °C (°F) 70 - 110
(158 - 230
70 - 110
(158 - 230
70 - 110
(158 - 230
CO2   Recirculation Yes Yes Yes
Extractor Changeover Valves Automatic Automatic Automatic
CO2   Pump Flowrate (LPH) 40-80 150 - 350 600 - 3000
Co-Solvent Pump Yes Yes Yes
CO2   Feeding & Recovery System Included Included Included
Available Certifications CE / U / U2
cGMP / ASME
BPE / UL / SIL-3
CE / U / U2
cGMP / ASME
BPE / UL / SIL-3
CE / U / U2
cGMP / ASME
BPE / UL / SIL-3
Area Required* (m/ft) 4.88 x 1.37 x 2.44 /
16 x 4.5 x 8
8 x 2.8 x 5.6 /
26 x 27 x 18.5
8 x 2.8 x 5.6 /
26 x 27 x 18.5
* All systems can be customized based on the factory layout

Common Bioactive Compounds Used in Cosmetics

Most relevant recent studies on the supercritical CO2 extraction of bioactive compounds from plant materials with application in cosmetic products:

Scientific Name Common Name Targeted Compounds Reported Activities SCO2 Extraction Conditions
Copaifera sp. Copaíba leaf Essential oils Antioxidant activities and antimicrobial activity, inhibition tyrosinase 35 MPa, 75 ◦C, 4 h
Synadenium grantii Hook f Mountain Tea Euphol, carvacrol, betulin aldehyde, and friedelan-3- one Antioxidant activity 15-25 MPa, 40-80 ◦C, 1 h, co-solvent EtOH
Sideritis sipylea Boiss - n-nonacosane, n-hexacosane and sideridiol, geranyl linalool Anti-tyrosinase and anti- elastase activity, antioxidant activity 30 MPa, 35-40 ◦C, 2 h, 25 g CO2/min
Prunus avium Sweet cherry stems Fatty acid derivatives and terpenes, catechin, chrysin, and Naringenin. Scavenging peroxyl free radicals 15 MPa, 40 ◦C, 1 h, co-solvent EtOH
Rubus idaeus L Red raspberry seeds Ω-3 fatty acids, tocophero Inhibition of aflatoxin activity 30 MPa, 40 ◦C, 3 h, 0.194 kg CO2/h,
Humulus Lupulus Stramonium Hops and Datura (leaves and flowers) Volatile oils, terpenes, terpenoids, fatty acids, and bitter acids Antibacterial activity against Escherichia coli 30 MPa, 70 ◦C, 5 h.
Camellia sinensis var. assamica Assam tea seeds Vegetable oil, phenolic compounds Low antioxidant activity 17.5-22.5 MPa, 40-60 ◦C, 110-170 L CO2/
Solidago gigantea Ait. Goldenrod Vegetable oil, phenols, chlorophyll Antibacterial activity Low level of cytotoxicity 20-80 MPa, 331.15-353.15 K, 3-7 kg CO2/h
Curcuma aromatica Salisb Wild turmeric Terpenes (p-cymene, β turmerone, curdione) Antioxidant, anti-inflammatory, anti-lipoxygenase activity and antibacterial activity 10-40 MPa, 40-65 ◦C, 1 h, 2 L CO2/min
Artocarpus heterophyllus Brazilian jackfruit 13,27-cycloursan-3- one,9,19 cyclolanost-24-en-3-ol and lanostero Antioxidant activity, antifungal activity 12-20 MPa, 40-50 ◦C, 150 min, 3.0 and 4.0 mL CO2/ min
Capsicum annuum L. Pepper seed Vegetable oil (linoleic, palmitic and oleic acids, tocopherol) Antioxidant activity 100 MPa, 40 ◦C, 2 h, 0.40 L/min CO2
Rosmarinus officinalis L Rosemary α-pinene, camphene, β-pinene, eucalyptol - 8.2 MPa, 35 ◦C, 30 min, 100 mL CO2/ min
Lavandula luisieri Spanish lavender Essential oil, rosmarinic acid, ursolic acid and oleanolic acid Antimicrobial activity, antioxidant activity 13 MPa, 30 g CO2/ min
Amaranthus spp Amaranth seed Squalene, triacylglycerols Antifungal activity 7 MPa, 65 ◦C, 18 kg CO2/h
Ocimum basilicum L. Basil Volatile oils Antioxidant activities Inhibition of acetylcholinesterase and tyrosinase 9 MPa, 313 K, 2.5 h, particle size 0.6 mm
Lycium ruthenicum Murr Russian box thorn Vegetable oil (unsaturated fatty acid, β carotene, tocopherol and total phenolics Antioxidant activity 26 MPa, 55 ◦C, 1 h, 80 L CO2/h, particle size: 0.6 mm
Picea Abies Norway spruce bark Resin acids, stilbens, astringin and piceid, β-sitosterol Antimicrobial and antifungal activity, antioxidant activity 48 MPa, 80 ◦C, 1 h, co-solvent EtOH
Lavandula Officinalis and Hypericum Perforatum Lavender and Centaury 1,2- benzenedicarboxylic acid, n-tetratriacontane, linalool, linalyl acetate Antimicrobial activity, antioxidant activity 10 MPa, 40 ◦C
Theobroma cacao Cocoa bean Phenols Antioxidant activity 20 MPa, 50 ◦C, 2 h 11 g CO2/min
Dialium cochinchinense Cinnamomum cambodianum, Gardenia angkorensis Pitard, Cananga latifolia Gagnep, and Oroxylum indicum (L.) Khmer medicinal plants (Pierre, Lecomte, Pitar, Finet, Kurz bark) Phenols Antioxidant activity 10 MPa, 150 ◦C, 4 h, 0.15 mL CO2/min
Zea mays Corn germ Lecithin Emulsification activity 30 MPa, 50 ◦C, 2 h, 25 L CO2/h
Sesamum indicum, L. Sesame seeds Γ-tocopherol, lignin, polyphenols Antioxidant activity 30 MPa, 60 ◦C, 1.5 h, 0.5 L CO2/min
Rubus fruticosus Blackberry seeds Phytosterols, tocopherol Antioxidant activity 30 MPa, 50 ◦C, 2.5 h, 80 kg CO2/h
Matricaria chamomilla Chamomile Umbelliferone, herniarin Antioxidant activity 30 MPa, 40 ◦C, 1.5 h, 2 kg CO2/h
Medicago sativa L. Lucerne or alfalfa Flavonoids, oleanolic acid equivalents, saponins Antioxidant activity 10 MPa, 50 ◦C, 1 h, 4 mL CO2/min, co-solvent EtOH
Hippophae rhamnoides L. Buckthorn Flavonoids, carotenoid, polyphenol, tocopherol Antioxidant activity Prolonged oxidant stability 40 ◦C, 30 MPa, 90 min, 0.5 L CO2/min
Eugenia involucrata Eugenia Essential oils β-elemene and bicyclogermacrene, vitamin E Antioxidant activity 20 MPa, 80 ◦C, 50-80 min
Opuntia ficus-indica L. Prickly pear Cactus, nopal Vegetable oil (vaccenic acid) Antioxidant and antibacterial activities 35 MPa, 40 ◦C, 8.5 kg CO2/h
Helichrysum italicum (Roth) G. Don, Angelica archangelica L., Lavandula officinalis L., Salvia officinalis L., Melilotus officinalis L., and Ruta graveolens L Immortelle, angelica, lavender, sage, sweet clover, rue Coumarin Antioxidant activity 15-30 MPa, 40 ◦C, 1.95 kg CO2/h
Rubus idaeus Raspberry pomace Phenols, linoleic and linolenic acid/td> Antioxidant activity 10-45 MPa, 30-60 ◦C, 30-120 min, 2 L CO2/min
Cytisus scoparius L. Broom Flavonoids, phenolic acids and phenolic aldehydes Antioxidant activity 25 MPa, 45 ◦C, 25 g CO2/min, co-solvent EtOH
Moringa oleifera Moringa Vegetable oil Antioxidant activity -40 MPa, 2-35 ◦C, 5 h 20 kg CO2/h
Zea mays Corn germ Lecithin Emulsification activity 30 MPa, 50 ◦C, 2 h, 25 L CO2/h
Coffea canephora L. Spent coffee bean Vegetable oil Sunscreen water resistance activity, photoprotective activity 25 MPa, 55 ◦C, 15 kg CO2/h, 1 h
Helichrysum italicum Immortelle Tremetone derivatives, squalene - 8-22 MPa, 36-64 ◦C, 1.94 kg CO2/h
Helichrysum italicum (Roth) Immortelle Scopoletin Antioxidant activity 7.93-22.07 MPa, 35.86-64.14 ◦C, 90 min, 1.94 kg CO2/h
Copaifera sp Copaíba Volatile oils Antioxidant activity, anti- inflammatory and neuroprotective effects 10-30 MPa, 40-60 ◦C, 0.000833 kg CO2/s
Vitis vinifera Grape marc Polyphenols Antioxidant activity 8 MPa, 20-80 ◦C, 4-10 min, 6 kg CO2/ h
Lippia sidoides Cham Pepper rosmarin seeds Polyphenols, flavonoids Antioxidant activity 40 MPa, 60 ◦C, 1.5 L CO2/min
Oryza sativa L. Rice bran Linoleic acid, oryzanol,policosanol, and tocotrienol 5-alpha-reductase inhibition 32 ◦C and 27 MPa, 240 min, 135 g CO2/ min
Calendula officinalis Marigold Pentacyclic triterpene monols, diols, monoester faradiol, diester myristic, palmitic and lauric acids Skin and wound healing, antimicrobial activity -
Hevea Brasiliensis Rubber seeds oil α-linolenic acid Moisturizing and stability in cosmetic products 60 ◦C, 30 MPa, 4 mL CO2/min
Cannabis sativa ssp. sativa Hemp seed Linoleic acid, γ-linolenic, and α-linolenic Moisturizing 30 and 40 MPa, 40, 60 and 80 ◦C
Sesamum indicum L. Sesame seed Oleic linoleic, palmitic and stearic acid Moisturizing 50 ◦C, 350 bar, 2 mL CO2/min
Triticum aestivum L. Wheat kernel Palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid Moisturizing 200-350 bar, 40-60 ◦C, 15-25 L CO2/h
Vitis vinifera L. Grape seed oil Oleic and linoleic acids and antioxidant-rich compounds Moisturizing 28-550 bar, 40 ◦C
Daucus carrota L. Carrot fruit Carotol, geranyl acetate,β-caryophyllene, daucol, essential oil Skin disorders, e.g. burns and furuncles 10 MPa, 40 ◦C
Borago officinalis L. Borage seed oil Free fatty acids: palmitic, stearic, oleic, linoleic acid, γ-linolenic acid Skin wounds healing, moisturizing 200 and 300 bar, 40-60 ◦C, 0.20 kg CO2/h
Oenothere biennis L. Evening primrose Γ-linolenic acid Skin wounds healing, moisturizing 200 and 300 bar, 40 and 60 ◦C, 0.17 kg CO2/h
Mangifera indica Mango leaves Phenolic compounds Anti-aging activity 25 MPa, 45 ◦C, 1 h, 3.96 kg CO2/s
Prinus dulcis Almond fruits Tochopherol, vegetable oil Moisturizing 420 bar, 50 ◦C, 2-3 h, 30 kg CO2,/h

Recent Projects

Pilot Scale Extraction System
  • Research for Herbal products Extraction
  • Capacity: 20L
  • Pressure Rating: 650 bar
  • Industry: Herbal Pharma Products
  • Location: India
Production Scale Extraction System
  • Essential Oil Extraction Plant
  • Capacity: 300L
  • Pressure Rating: 350 bar
  • Industry: Essential Oil
  • Location: Indonesia

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